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Nutrients 11:2101
In human thyroid cancer, GPx3 is frequently methylated, and the expression of GPx3 is regulated by methylation of the promoter region, and this methylation is related to tumor size and lymph node metastasis through the inhibition of Wnt/-catenin signaling [100]
In addition, clinical studies have suggested that DSIP may also have beneficial effects on stage-4 sleep, which is also known as REM sleep and the phase when dreaming occurs [3, 4]
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